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PhytoCellTec™ Symphytum

Speed up your skin renewal through stem cell activation

About PhytoCellTec™ Symphytum

PhytoCellTec™ Symphytum is based on stem cells from comfrey roots. Comfrey is an old medicinal plant known for its healing properties. It has clearly been shown to boost the regenerative power of epidermal stem cells and their ability to build new tissue. Indeed, even in pro-aging conditions, PhytoCellTec™ Symphytum has been proven to increase the thickness of the epidermis (+ by 88 %), resulting in a healthy, supple skin with an improved barrier function.





Mibelle Biochemistry has developed a novel plant cell culture technology (PhytoCellTec™) that enables the large-scale cultivation of callus (stem) cells from rare and protected plant species, such as Symphytum officinale. The PhytoCellTec™ technology, which was recognized at the UN Conference Rio+20 as an Eco breakthrough, delivers a highly sustainable sourcing of this active. You can find further information on our PhytoCellTec™ website.

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Proven Efficacy

  • Inhibition of the age-related decrease of the regenerative capacity of skin stem cells

  • Improvement of the capacity to build new tissues in a pro-aging medium (3D epidermis)

  • Inhibition of the age-related thinning of the epidermis (3D epidermis)

  • Increase of skin renewal

  • Smoothing effect

  • In vivo study

  • In vitro study

Claim Ideas

  • Recharges youthfulness of skin stem cell
  • Boosts cell turnover to rejuvenate the skin from the inside out
  • Maintains the regenerative capacity, even as the years pass by
  • Reveals a fresher and smoother skin

Plant Source


Comfrey (Symphytum officinale) is a perennial herb with large, hairy leaves that bears small bell-shaped flowers of various colors. Comfrey has been used since ancient times: The ancient Romans and Greeks recommended comfrey for wound healing and broken bones as well as inflammatory and traumatic lesions of muscles and joints.

INCI (EU/PCPC) Declaration

Symphytum Officinale Callus Culture Extract (and) Isomalt (and) Lecithin (and) Sodium Benzoate (and) Aqua / Water

Recommended Use Level

0.4 – 1 %

Scientific Publications