Liposomes and Nanoemulsions

Advanced delivery technologies are essential for unlocking the full potential of modern cosmetic and active ingredients. Liposome and nanoemulsion technologies are scientifically proven systems that enhance ingredient stability, skin compatibility, and bioavailability. This helps actives perform where they matter most.

Mibelle Biochemistry has more than 30 years of experience in the encapsulation of highly effective active ingredients for a wide range of applications, from skin and scalp care to hair care and even food supplements.

A significant share of Mibelle Biochemistry’s actives integrates advanced delivery systems based on liposomal technology. This strategic approach reflects one of our core principles: maximizing the bioavailability of active ingredients. The platform technology is also ideally suited for customized products, as a wide variety of compounds can be effectively encapsulated in liposomes and nanoemulsions. 

Liposomes are microscopic vesicles that are composed of phospholipids, which closely resemble the natural lipid structure of human skin. This biomimetic design enables liposomes to encapsulate both water‑soluble and lipid‑soluble actives and transport them efficiently into the skin.

Mibelle Biochemistry leverages this technology, in particular, to create high-end plant extracts and plant stem cell extracts. This approach ensures the full spectrum of valuable components - such as lipophilic cell membranes and water-soluble actives from plant cells - remains optimally solubilized and highly bioavailable, hence unlocking their full efficacy.

By protecting sensitive ingredients from degradation and controlling their release, liposomes significantly improve the stability and efficacy of actives. Their affinity with the skin barrier enables enhanced penetration into targeted skin layers, while maintaining excellent skin tolerance. As a result, liposome technology supports prolonged activity, optimized performance, and gentle delivery - even for highly potent or sensitive ingredients.

Key benefits of liposome technology include:

• Enhanced penetration and bioavailability of active ingredients
• Protection of sensitive actives from oxidation and degradation
• Controlled and sustained release for long‑lasting efficacy
• High skin compatibility due to biomimetic lipid structure

Nanoemulsions are extremely fine oil‑in‑water or water‑in‑oil dispersions, with droplet sizes that are typically in the nanometer range. Their exceptionally small particle size creates a transparent or translucent system and provides a very large surface area for interaction with the skin.

This technology enables the uniform distribution of lipophilic ingredients, improves absorption, and enhances sensory properties such as lightness and fast skin feel. Nanoemulsions also offer high formulation stability, which makes them ideal for delivering active ingredients in both an efficient and consistent way.

Key benefits of nanoemulsion technology include:

• Improved absorption and fast delivery of actives
• Enhanced formulation stability and homogeneity
• Lightweight, non‑greasy sensory profile
• Optimized performance of poorly soluble ingredients

Performance‑Driven Delivery Systems

By combining scientific expertise with cutting‑edge delivery technologies, liposome and nanoemulsion systems enable targeted, efficient, and consumer‑relevant product performance. These technologies support the development of innovative cosmetic and dermocosmetic solutions that meet the highest standards for efficacy, safety, and sensory appeal.