CM-Glucan Forte

Rebalances the skin’s immune system

Hydration / Barrier

Hydration / Barrier

Redness / Sensitive Skin / Wellbeing

Redness / Sensitive Skin / Wellbeing

Skin Defense

Skin Defense

CM-Glucan Forte is a special Beta Glucan from baker’s yeast (Magnesium Carboxymethyl Beta-Glucan). This single molecule product is designed to rebalance the immune system of the skin, soothe irritations and strengthen the skin barrier.

Nowadays, we are experiencing an increase in allergies and allergic skin reactions such as eczemas and atopic dermatitis – a consequence of the exaggerated hygiene in our modern, developed world. Instead of reacting by a simple Th1 response where macrophages solve the problem, the skin reacts by an exaggerated Th2 response with the involvement of B cells and production of IgE antibodies that pave the way to an allergy.


Product Documents


ß-(1-3)-glucan purified from the cell walls of common baker’s yeast  is a physiologically active compound. It fights infections and is probably one of the most studied natural immunomodulators.

Mibelle Biochemistry has been a pioneer in terms of purifying ß-glucans from the cell walls of baker’s yeast and in modifying the molecule for an improved water-solubility. In CM-Glucan Forte (Magnesium Carboxymethyl Beta-Glucan ), the divalent magnesium ions enhance the structural stability of the large molecule. Moreover, Mg++ ions bind water molecules, exhibit anti-inflammatory properties and were shown to positively influence epidermal proliferation and differentiation.

Supplier of Active Ingredients
Proven efficacy

In vitro

  • Reduces IgE antibody production
  • Reduces the release of IL-1α
  • Reduces IL-8 expression (indicator for atopic skin)
  • Inhibits adhesion of Staphylococcus aureus bacteria to skin

In vivo

  • Strengthens the skin barrier
  • Alleviates the 6 symptoms of eczema
  • Soothes irritated skin
  • Calms sensitive and itching skin
  • Alleviates symptoms of atopic skin in less than one week
  • Personal trainer to strengthen sensitive skin
INCI (EU/PCPC) Declaration

Magnesium Carboxymethyl Beta-Glucan



  • Powder
  • Water-soluble
  • Single substance
  • Without alcohol
  • Without preservatives

Recommended use level

  • 0.02 – 0.1 %
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