PhytoCellTec™ Malus Domestica Skin

Plant stem cells for skin stem cell protection



Antioxidant / Energizing

Antioxidant / Energizing



PhytoCellTec™ Malus Domestica is a patented liposomal preparation of apple stem cells derived from the ‘Uttwiler Spätlauber’, a rare Swiss apple variety. These apple stem cells are rich in epigenetic factors and metabolites, which ensures the longevity of skin cells. PhytoCellTec™ Malus Domestica has been shown to protect skin stem cells while also delaying the senescence of hair follicles. PhytoCellTec™ Malus Domestica succeeds in delivering a revolutionary anti-aging performance for real rejuvenation.

Mibelle Biochemistry has developed a plant cell culture technology (PhytoCellTec™) that enables the large-scale cultivation of callus (stem) cells from rare or protected plants, such as the ‘Uttwiler Spätlauber’ apple variety. The PhytoCellTec™ technology, which was recognized at the UN Conference Rio+20 as an Eco breakthrough, delivers a highly sustainable sourcing of this active. You can find further information on our PhytoCellTec™ website.

PhytoCellTec™ Malus Domestica was the first ingredient based on plant stem cells on the cosmetic market. The topical use of PhytoCellTec™ Malus Domestica is patented in the USA (US 9,155,916 B2 / US 8,580,320 B2),EU (1 985 280 B1), in Switzerland (CH 715 456 B1) and in Korea (10-1470632).


x xcosmos   x x x    Nature

Product Documents

Plant Source

Uttwiler Spätlauber is a variety of a Swiss apple (Malus domestica) that is derived from a seedling planted in the middle of the 18th century. It was very famous for its excellent storability without shriveling. Uttwiler Spätlauber apples have especially long-living tissue stem cells, while their specific composition of metabolites leads to incredible storability and longevity properties.

Plant source
Discover the BBC documentary on the Uttwiler Spätlauber and our PhytoCellTec™ technology
Proven efficacy

In vitro

  • Increases the colony forming efficiency of epidermal stem cells
  • Helps skin cells to maintain the capacity to build new tissues (3D epidermis)
  • Increases skin density
  • Increases the vitality of the epidermal stem cells
  • Reverses signs of senescence in fibroblasts

In vivo

  • Anti-wrinkle effet on the eye contour area
  • Protects longevity of skin stem cells
  • Increases the vitality of skin stem cells
  • Combats chronological aging
  • Increases the regenerative potential of the skin
  • Improves both wrinkles and skin firmness in the eye contour area
INCI (EU/PCPC) Declaration

PhytoCellTec™ Malus Domestica (standard version): Malus Domestica Fruit Cell Culture Extract (and) Xanthan Gum (and) Glycerin (and) Lecithin (and) Phenoxyethanol (and) Aqua / Water

PhytoCellTec™ Md or (powder version, without preservatives, 10-fold concentrated, COSMOS approved *, NATRUE approved version): Malus Domestica Fruit, Cell Culture Extract (and) Isomalt (and) Aqua / Water

PhytoCellTec™ MD lf (lecithin-free version): Malus Domestica Fruit Cell Culture Extract (and) Xanthan Gum (and) Sodium Benzoate (and) Aqua / Water 

*Raw material approved by ECOCERT GREENLIFE in accordance with the COSMOS Standard



  • Water soluble
  • Without alcohol
  • Version without preservatives available
  • Version without lecithin available

Recommended use level

  • 2 – 5 %
More information about PhytoCellTec™ Malus Domestica Skin

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